Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome.

Journal of the American College of Cardiology - 4 Mar 2008

Schwartz Peter J, Vanoli Emilio, Crotti Lia, Spazzolini Carla, Ferrandi Chiara, Goosen Althea, Hedley Paula, Heradien Marshall, Bacchini Sara, Turco Annalisa, La Rovere Maria Teresa, Bartoli Antonella, George Alfred L, Brink Paul A

Abstract excerpt

OBJECTIVES: The purpose of this study was to test the hypothesis that differences in autonomic responses might modify clinical severity in long QT syndrome type 1 (LQT1) patients, those with KCNQ1 mutations and reduced I(Ks), in whom the main arrhythmia trigger is sympathetic activation. BACKGROU...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autonomic Nervous System
Share to Genetic Heterogeneity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Rate

Share to KCNQ1 Potassium Channel

Share to Long QT Syndrome

Share to Receptors, Adrenergic

Share to Risk Factors

Share to Severity of Illness Index

Source

Identifiers

PMID: 18308161
DOI: 10.1016/j.jacc.2007.09.069

Genes

KCNQ1
ADRB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18308161-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome.PMID 18308161Read ↗

Genomics of Cardiovascular Measures of Autonomic Tone.Semantic proximity Read ↗

Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.Semantic proximity Read ↗

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.Semantic proximity Read ↗

Heart rate-dependent variability of cardiac events in type 2 congenital long-QT syndrome.Semantic proximity Read ↗

Low blood pressure phenotype underpins the tendency to reflex syncopeSemantic proximity Read ↗

Genetic Basis and Prognostic Value of Exercise QT Dynamics.Semantic proximity Read ↗

Adrenergic receptors gene polymorphisms and autonomic nervous control of heart and vascular tone.Semantic proximity Read ↗

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.Semantic proximity Read ↗

Bradycardia in Athletes: Prevalence, Mechanisms, and Risks.Semantic proximity Read ↗

Gene-specific effect of beta-adrenergic blockade on corrected QT interval in the long QT syndrome.Semantic proximity Read ↗

β-1 and β-2 adrenergic receptor polymorphism and association with cardiovascular response to orthostatic screening.Semantic proximity Read ↗

Comparison of QT peak and QT end interval responses to autonomic adaptation in asymptomatic LQT1 mutation carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.