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Article

Epinephrine unmasks latent mutation carriers with LQT1 form of congenital long-QT syndrome.

Journal of the American College of Cardiology - 19 Feb 2003

Shimizu Wataru, Noda Takashi, Takaki Hiroshi, Kurita Takashi, Nagaya Noritoshi, Satomi Kazuhiro, Suyama Kazuhiro, Aihara Naohiko, Kamakura Shiro, Sunagawa Kenji, Echigo Shigeyuki, Nakamura Kazufumi, Ohe Tohru, Towbin Jeffrey A, Napolitano Carlo, Priori Silvia G

Abstract excerpt

OBJECTIVES: This study was designed to test the hypothesis that epinephrine infusion may be a provocative test able to unmask nonpenetrant KCNQ1 mutation carriers. BACKGROUND: The LQT1 form of congenital long QT syndrome is associated with high vulnerability to sympathetic stimulation and appears with incomplete penetrance. METHODS: The 12-lead electrocardiographic parameters before and after epinephrine infusion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12598076
DOI: 10.1016/s0735-1097(02)02850-4

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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