Article
CD9 tetraspanin generates fusion competent sites on the egg membrane for mammalian fertilization
20 Jun 2011
Abstract excerpt
CD9 tetraspanin is the only egg membrane protein known to be essential for fertilization. To investigate its role, we have measured, on a unique acrosome reacted sperm brought in contact with an egg, the adhesion probability and strength with a sensitivity of a single molecule attachment. Probing the binding events at different locations of wild-type egg we described different modes of interaction. Here, we show...
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