Cleavage of concatemeric DNA at the internal junction of "translocation" mutants of pseudorabies virus and inversion of their L component appear to be linked.

doi:10.1016/0042-6822(92)90310-l

Article

Cleavage of concatemeric DNA at the internal junction of "translocation" mutants of pseudorabies virus and inversion of their L component appear to be linked.

Virology - 1 Mar 1992

Kupershmidt S, Rall G F, Lu Z Q, Ben-Porat T

Abstract excerpt

When pseudorabies virus (PrV) strains are grown in chicken embryo fibroblasts (CEF), variants ("translocation" mutants) arise in which there is a duplication of the leftmost sequences of the genome and their translocation in inverted orientation next to the internal inverted repeat bracketing the S component. In these variants, the UL becomes bracketed by inverted repeats and is found in two orientations relative...

Topics

Animals
Base Sequence
Blotting, Southern
Cells, Cultured
Chick Embryo
Chromosome Inversion
DNA, Viral
Genetic Linkage
Genome, Viral
Herpesvirus 1, Suid
Molecular Sequence Data

Cleavage of concatemeric DNA at the internal junction of "translocation" mutants of pseudorabies virus and inversion of their L component appear to be linked.

Abstract excerpt

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