Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Murine coronavirus nonstructural protein ns2 is not essential for virus replication in transformed cells

1 Oct 1990

Abstract excerpt

Two isolates of the murine hepatitis virus (MHV) strain JHM, which differed in their ability to express the nonstructural gene product ns2, were characterized. The MHV Wb3 isolate encodes a 30,000-molecular-weight ns2 protein that can be readily detected in infected cells by using a specific monoclonal antibody, MAb 2A. The MHV Wb1 isolate is a deletion mutant that lacks a functional ns2 gene and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2168966
DOI: 10.1128/jvi.64.10.4784-4791.1990

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Murine coronavirus nonstructural protein ns2 is not essential for virus replication in transformed cellsPMID 2168966Read ↗

The nsp2 Replicase Proteins of Murine Hepatitis Virus and Severe Acute Respiratory Syndrome Coronavirus Are Dispensable for Viral ReplicationSemantic proximity Read ↗

Murine coronaviruses encoding nsp2 at different genomic loci have altered replication, protein expression, and localization.Semantic proximity Read ↗

Recombinant Mouse Hepatitis Virus Strain A59 from Cloned, Full-Length cDNA Replicates to High Titers In Vitro and Is Fully Pathogenic In VivoSemantic proximity Read ↗

Organ-Specific Attenuation of Murine Hepatitis Virus Strain A59 by Replacement of Catalytic Residues in the Putative Viral Cyclic Phosphodiesterase ns2Semantic proximity Read ↗

Respiratory Syncytial Virus That Lacks Open Reading Frame 2 of the M2 Gene (M2-2) Has Altered Growth Characteristics and Is Attenuated in RodentsSemantic proximity Read ↗

Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine CoronavirusSemantic proximity Read ↗

Genetic analysis of Murine hepatitis virus nsp4 in virus replication.Semantic proximity Read ↗

Characterization of attenuated mutants of MHV3: importance of the E2 protein in organ tropism and infection of isolated liver cells.Semantic proximity Read ↗

The NS2 Polypeptide of Parvovirus MVM Is Required for Capsid Assembly in Murine CellsSemantic proximity Read ↗

Heterogeneity of subgenomic mRNAs of a mutant mouse hepatitis virus strain JHM2C.Semantic proximity Read ↗

The small nonstructural protein (NS2) of the parvovirus minute virus of mice is required for efficient DNA replication and infectious virus production in a cell-type-specific mannerSemantic proximity Read ↗

The Small Envelope Protein E Is Not Essential for Murine Coronavirus ReplicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.