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Article

Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains.

Virology - 1 Feb 1994

Bonilla P J, Gorbalenya A E, Weiss S R

Abstract excerpt

Gene 1, the putative RNA replicase gene of coronaviruses, is expressed via two large overlapping open reading frames (ORF 1a and ORF 1b). We have determined the nucleotide sequence of ORF 1a, encoded within the first 13.7 kb of gene 1, for the coronavirus mouse hepatitis virus strain A59 (MHV-A59). Putative papain-like protease domains, a picornavirus 3C-like protease domain, two hydrophobic domains, and a domain...

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Identifiers

PMID: 8291254
DOI: 10.1006/viro.1994.1088
PMCID: PMC7130950

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