Article
Influenza A virus hemagglutinin containing basolateral localization signal does not alter the apical budding of a recombinant influenza A virus in polarized MDCK cells.
Virology - 5 Jan 2003
Barman Subrata, Adhikary Lopa, Kawaoka Yoshihiro, Nayak Debi P
Abstract excerpt
Morphogenesis of influenza virus is a complex multistep process involving transport of all viral components as either individual or subviral components to the specified assembly site and interaction among the viral components in an ordered fashion to initiate the budding process. Envelope glycoprotein(s) is believed to be the major determinant in selecting the viral budding site since the majority of the viral...
Topics
- Animals
- Cell Polarity
- Cells, Cultured
- Dogs
- Endocytosis
- Hemagglutinin Glycoproteins, Influenza Virus
- Influenza A virus
- Microscopy, Electron
- Mutation
- Transfection
- Virion
- Virus Assembly
- Virus Replication