Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Both genes for EF-Tu in Salmonella typhimurium are individually dispensable for growth.

Journal of molecular biology - 5 Sept 1990

Hughes D

Abstract excerpt

Each of the two genes encoding EF-Tu in Salmonella typhimurium has been inactivated using a mini-Mu MudJ insertion. Eleven independently isolated insertions are described, six in tufA and five in tufB. Transduction analysis shows that the inserted MudJ is 100% linked to the appropriate tuf gene. A mutant strain with electrophoretically distinguishable EF-TuA and EF-TuB was used to show, on two-dimensional gels,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Cloning, Molecular
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Genes, Bacterial

Share to Genotype

Share to Plasmids

Share to Restriction Mapping

Source

Identifiers

PMID: 2168947
DOI: 10.1016/S0022-2836(05)80093-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Both genes for EF-Tu in Salmonella typhimurium are individually dispensable for growth.PMID 2168947Read ↗

A single amino acid substitution in elongation factor Tu disrupts interaction between the ternary complex and the ribosome.Semantic proximity Read ↗

Error-prone EF-Tu reduces in vivo enzyme activity and cellular growth rate.Semantic proximity Read ↗

Homologous recombination between the tuf genes of Salmonella typhimurium.Semantic proximity Read ↗

Divergence among genes encoding the elongation factor Tu of Yersinia Species.Semantic proximity Read ↗

Bacterial elongation factors EF-Tu, their mutants, chimeric forms, and domains: isolation and purification.Semantic proximity Read ↗

Co-evolution of the tuf genes links gene conversion with the generation of chromosomal inversions.Semantic proximity Read ↗

Mutants of the RNA-processing enzyme RNase E reverse the extreme slow-growth phenotype caused by a mutant translation factor EF-Tu.Semantic proximity Read ↗

Genetic engineering, isolation and characterization of a truncated Escherichia coli elongation factor Tu comprising domains 2 and 3.Semantic proximity Read ↗

Missense substitutions lethal to essential functions of EF-Tu.Semantic proximity Read ↗

EF-Tu from the enacyloxin producing Frateuria W-315 strain: Structure/activity relationship and antibiotic resistance.Semantic proximity Read ↗

Antisuppression by mutations in elongation factor Tu.Semantic proximity Read ↗

Mutants of EF-Tu defective in binding aminoacyl-tRNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.