Error-prone EF-Tu reduces in vivo enzyme activity and cellular growth rate.

doi:10.1111/j.1365-2958.1991.tb00733.x

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Article

Error-prone EF-Tu reduces in vivo enzyme activity and cellular growth rate.

Molecular microbiology - 1 Mar 1991

Hughes D

Abstract excerpt

Mutations in Salmonella typhimurium encoding error-prone EF-Tu (tufA8, tufB103) enhance translational error levels and also cause a reduced growth rate. The relative changes in error level and growth rate are inversely related and dependent on the status of the two tuf genes. Possible causes of t...

Topics

Cell Division
Mutation
Peptide Elongation Factor Tu
Phenotype
Protein Biosynthesis
RNA, Bacterial
RNA, Transfer
Ribosomes
Salmonella typhimurium
beta-Galactosidase

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