Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGF-β1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2011

Wang Jing, Chen Jian, Zhang Kailiang, Zhao Yuan, Nör Jacques E, Wu Junzheng

Abstract excerpt

BACKGROUND: Patients with mucoepidermoid carcinoma exhibit poor long-term prognosis because of the lack of therapeutic strategies that effectively block tumor progression. We have previously characterized the Ms cells as a highly metastatic mucoepidermoid carcinoma cell line that expresses high levels of transforming growth factor β1 (TGF-β1). Here, we studied the effect of suppressing TGF-β1 by RNA silencing on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biocompatible Materials
Share to Drug Combinations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Laminin

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Neoplasm Transplantation

Share to Proteoglycans

Share to Salivary Gland Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 21689159
DOI: 10.1111/j.1600-0714.2011.01051.x
PMCID: PMC3723136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGF-β1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells.PMID 21689159Read ↗

Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell CarcinomaSemantic proximity Read ↗

Development of a highly metastatic model that reveals a crucial role of fibronectin in lung cancer cell migration and invasion.Semantic proximity Read ↗

Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancerSemantic proximity Read ↗

Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis.Semantic proximity Read ↗

Laminin-γ2-NR6A1 Fusion Protein Promotes Metastatic Potential in Non-Small-Cell Lung Carcinoma Cells without Epidermal Growth Factor Receptor Mutation.Semantic proximity Read ↗

Enforced Expression of MCAM/MUC18 Increases In vitro Motility and Invasiveness and In vivo Metastasis of Two Mouse Melanoma K1735 Sublines in a Syngeneic Mouse ModelSemantic proximity Read ↗

MUC4, a Multifunctional Transmembrane Glycoprotein, Induces Oncogenic Transformation of NIH3T3 Mouse Fibroblast CellsSemantic proximity Read ↗

Critical roles of Wnt5a–Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ΔNp63β-mediated epithelial–mesenchymal transitionSemantic proximity Read ↗

RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells.Semantic proximity Read ↗

TGFβ, Fibronectin and Integrin α5β1 Promote Invasion in Basal Cell CarcinomaSemantic proximity Read ↗

Uveal melanoma cell lines Mel270 and 92.1 exhibit a mesenchymal phenotype and sensitivity to the cytostatic effects of transforming growth factor beta in vitro.Semantic proximity Read ↗

MUC1 alters oncogenic events and transcription in human breast cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.