Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enforced Expression of MCAM/MUC18 Increases In vitro Motility and Invasiveness and In vivo Metastasis of Two Mouse Melanoma K1735 Sublines in a Syngeneic Mouse Model

1 Nov 2008

Abstract excerpt

Human MCAM/MUC18 has been shown to increase metastasis of human melanoma cells in xenograft mouse systems. To be more relevant to understanding the progression of clinical melanoma and for designing better preclinical therapeutic trials, it is highly desirable to establish a syngeneic mouse model for studying the mechanisms of MCAM/MUC18-mediated tumorigenesis and metastasis of melanoma cells. To reach this goal,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Immunotherapy and Immune Responses
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19010815
DOI: 10.1158/1541-7786.mcr-07-2200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enforced Expression of MCAM/MUC18 Increases In vitro Motility and Invasiveness and In vivo Metastasis of Two Mouse Melanoma K1735 Sublines in a Syngeneic Mouse ModelPMID 19010815Read ↗

Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cellsSemantic proximity Read ↗

METCAM/MUC18 augments migration, invasion, and tumorigenicity of human breast cancer SK-BR-3 cellsSemantic proximity Read ↗

Sequential molecular analysis of circulating MCAM/MUC18 expression: a promising disease biomarker related to clinical outcome in melanomaSemantic proximity Read ↗

TGF-β1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells.Semantic proximity Read ↗

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells.Semantic proximity Read ↗

A Subset of Host B Lymphocytes Controls Melanoma Metastasis through a Melanoma Cell Adhesion Molecule/MUC18-Dependent Interaction: Evidence from Mice and HumansSemantic proximity Read ↗

Predominance of the metastatic phenotype in hybrids formed by fusion of mouse and human melanoma clones.Semantic proximity Read ↗

Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.Semantic proximity Read ↗

Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior.Semantic proximity Read ↗

Expression of complete keratin filaments in mouse L cells augments cell migration and invasion.Semantic proximity Read ↗

Site-directed Mutagenesis of nm23-H1Semantic proximity Read ↗

Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.