Article
KRAS polymorphisms are associated with survival of CRC in Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016
Dai Qiong, Wei Hui Lian, Huang Juan, Zhou Tie Jun, Chai Li, Yang Zhi-Hui
Abstract excerpt
rs12245, rs12587, rs9266, rs1137282, rs61764370, and rs712 of KRAS oncogene are characterized in the 3'UTR. The study highlights the important role of these polymorphisms playing in the susceptibility, oxaliplatin-based chemotherapy sensitivity, progression, and prognosis of CRC. Improved multiplex ligation detection reaction (iMLDR) technique is used for genotyping. An unconditional logistic regression model was...
