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Article

KRAS SNPs are related to colorectal cancer susceptibility and survival in Chinese people.

Biomarkers in medicine - 1 Jan 2020

Liu XiuLan, Yang Guangji, Huang Juan, Chai Li, Liu Xun, Dai Qiong, Yang ZhiHui

Abstract excerpt

Aim:KRAS SNPs may increase KRAS transcription and KRAS levels. SNPs of KRAS 3'UTR can affect carcinoma risk and prognosis. Materials & methods: The rs8720 and rs7960917 in KRAS 3'UTR for colorectal carcinoma (CRC) risk and survival were investigated in a case-control study. Association between SNPs and CRC risk, survival analysis were analyzed by an unconditional logistic regression model, log-rank test,...

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PMID: 31729889
DOI: 10.2217/bmm-2019-0172

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