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Article

When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?

Annals of surgical oncology - 1 Aug 2009

Calva Daniel, O'Dorisio Thomas M, Sue O'Dorisio M, Lal Geeta, Sugg Sonia, Weigel Ronald J, Howe James R

Abstract excerpt

BACKGROUND: Mutations in the RET proto-oncogene cause multiple endocrine neoplasia type 2A (MEN2A), and prophylactic thyroidectomy has generally been recommended before the age of 5 years. Patients with codon 609 mutations develop MTC at a later age and therefore the timing of prophylactic thyroi...

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Source

Identifiers

PMID: 19472011
DOI: 10.1245/s10434-009-0524-3

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19472011-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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