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Article

Quinolone Resistance: Much More than Predicted

1 Jan 2011

Abstract excerpt

Since quinolones are synthetic antibiotics, it was predicted that mutations in target genes would be the only mechanism through which resistance could be acquired, because there will not be quinolone-resistance genes in nature. Contrary to this prediction, a variety of elements ranging from efflux pumps, target-protecting proteins, and even quinolone-modifying enzymes have been shown to contribute to quinolone...

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Identifiers

PMID: 21687414
DOI: 10.3389/fmicb.2011.00022

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