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Article

Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies

1 Jan 2012

Abstract excerpt

Resistance to quinolones and fluoroquinolones is being increasingly reported among human but also veterinary isolates during the last two to three decades, very likely as a consequence of the large clinical usage of those antibiotics. Even if the principle mechanisms of resistance to quinolones are chromosome-encoded, due to modifications of molecular targets (DNA gyrase and topoisomerase IV), decreased...

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PMID: 22347217
DOI: 10.3389/fmicb.2012.00024

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