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Article

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy.

Haematologica - 1 Oct 2011

Barragán Eva, Montesinos Pau, Camos Mireia, González Marcos, Calasanz Maria J, Román-Gómez José, Gómez-Casares Maria T, Ayala Rosa, López Javier, Fuster Óscar, Colomer Dolors, Chillón Carmen, Larrayoz María J, Sánchez-Godoy Pedro, González-Campos José, Manso Félix, Amador Maria L, Vellenga Edo, Lowenberg Bob, Sanz Miguel A

Abstract excerpt

BACKGROUND: Fms-like tyrosine kinase-3 (FLT3) gene mutations are frequent in acute promyelocytic leukemia but their prognostic value is not well established. DESIGN AND METHODS: We evaluated FLT3-internal tandem duplication and FLT3-D835 mutations in patients treated with all-trans retinoic acid and anthracycline-based chemotherapy enrolled in two subsequent trials of the Programa de Estudio y Tratamiento de las...

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Identifiers

PMID: 21685470
DOI: 10.3324/haematol.2011.044933
PMCID: PMC3186308

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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