Article
Inferior prognostic outcome in acute promyelocytic leukemia with alterations of FLT3 gene.
Leukemia & lymphoma - 1 Sept 2006
Yoo Soo Jin, Park Chan Jeoung, Jang Seongsoo, Seo Eul-Ju, Lee Kyoo-Hyung, Chi Hyun Sook
Abstract excerpt
Alterations of the FLT3 gene, in the form of internal tandem duplications (ITD) and D835 point mutations, occur frequently in acute promyelocytic leukemia (APL). We therefore evaluated the frequency and clinical relevance of FLT3 aberrations in a series of Korean APL patients. We assayed FLT3 ITD...
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