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The Arg399Gln polymorphism in the XRCC1 gene is associated with increased risk of hematological malignancies.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2015

Du Liang, Liu Yuqi, Xue Pei, Song Chenxi, Shen Jiani, He Qing, Peng Yuanling, Tong Xiang, Tang Lizhi, Zhang Yonggang

Abstract excerpt

The associations between the Arg399Gln polymorphism in X-ray repair cross-complementing gene 1 (XRCC1) gene and the risk of hematological malignancies have been extensively investigated. However, the results were inconsistent. The objective of the current study is to investigate the association by meta-analysis. We searched PubMed database, Embase database, CNKI database, Wanfang database, and Weipu database,...

Topics

DNA-Binding Proteins
Ethnicity
Genetic Association Studies
Genetic Predisposition to Disease
Hematologic Neoplasms
Humans
Leukemia
Polymorphism, Single Nucleotide
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 25619474
DOI: 10.1007/s13277-015-3099-6

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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The Arg399Gln polymorphism in the XRCC1 gene is associated with increased risk of hematological malignancies.PMID 25619474Read ↗

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Association between the XRCC1 Arg399Gln polymorphism and risk of cancer: evidence from 297 case-control studies.Semantic proximity Read ↗

An updated meta-analysis between the association of XRCC1 Arg399Gln polymorphism and hepatocellular carcinoma risk.Semantic proximity Read ↗

X-ray repair cross-complementing group 1 polymorphisms and cancer risks in Asian populations: a mini review.Semantic proximity Read ↗

The XRCC1 Arg399Gln genetic polymorphism contributes to hepatocellular carcinoma susceptibility: an updated meta-analysis.Semantic proximity Read ↗

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Association of XRCC1 Arg399Gln polymorphism with bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

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