Article
Anatomy of disturbed sleep in pallido-ponto-nigral degeneration.
Annals of neurology - 1 Jun 2011
Spector Andrew R, Dugger Brittany N, Wszolek Zbigniew K, Uitti Ryan J, Fredrickson Paul, Kaplan Joseph, Boeve Bradley F, Dickson Dennis W, Strongosky Audrey, Lin Siong-Chi
Abstract excerpt
OBJECTIVE: Pallido-ponto-nigral degeneration (PPND), caused by an N279K mutation of the MAPT gene, is 1 of a family of disorders collectively referred to as frontotemporal dementia and parkinsonism linked to chromosome 17. This study aims to characterize the nature of the sleep disturbance in PPND and compare these findings to those in other progressive neurological illnesses. Pathological findings are also...
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