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Metabolic reprogramming of macrophages in the context of type 2 diabetes

15 Oct 2024

Abstract excerpt

Type 2 diabetes (T2D) is associated with insulin resistance and progressive dysfunction of β-pancreatic cells, leading to persistent hyperglycemia. Macrophages play a crucial role in this context, influencing both the development and progression of insulin resistance. These innate immune cells respond to inflammatory stimuli and reprogram their metabolism, directly impacting the pathophysiology of T2D....

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PMID: 39407333
DOI: 10.1186/s40001-024-02069-y

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