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Article

Mutational analysis of ligand binding activity of beta 2 adrenergic receptor expressed in Escherichia coli.

The EMBO journal - 1 Sept 1990

Breyer R M, Strosberg A D, Guillet J G

Abstract excerpt

A novel in situ screening procedure was used to identify neutral mutations in the human beta 2 adrenergic receptor (beta 2AR). The coding region of the human beta 2AR gene was subcloned under transcriptional control of an inducible T7 promoter and used to transform Escherichia coli. Colonies expressing the beta 2AR bound the radiolabeled antagonist [125I]iodocyanopindolol and could be identified by...

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Identifiers

PMID: 2167830
DOI: 10.1002/j.1460-2075.1990.tb07453.x
PMCID: PMC551972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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