Article
Ligand binding to the beta-adrenergic receptor involves its rhodopsin-like core.
Nature - 1 Jan 2000
Dixon R A, Sigal I S, Rands E, Register R B, Candelore M R, Blake A D, Strader C D
Abstract excerpt
Recently the genes for several hormone receptors that interact with guanine nucleotide binding proteins (G proteins) have been cloned, including the hamster beta 2-adrenergic receptor (beta 2AR), a human beta AR, the turkey erythrocyte beta AR and the porcine muscarinic acetylcholine receptor (MAR). All these receptors share some amino-acid homology with rhodopsin, particularly in 7 hydrophobic stretches of...
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