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Article

Ligand binding to the beta-adrenergic receptor involves its rhodopsin-like core.

Nature - 1 Jan 2000

Dixon R A, Sigal I S, Rands E, Register R B, Candelore M R, Blake A D, Strader C D

Abstract excerpt

Recently the genes for several hormone receptors that interact with guanine nucleotide binding proteins (G proteins) have been cloned, including the hamster beta 2-adrenergic receptor (beta 2AR), a human beta AR, the turkey erythrocyte beta AR and the porcine muscarinic acetylcholine receptor (MAR). All these receptors share some amino-acid homology with rhodopsin, particularly in 7 hydrophobic stretches of...

Topics

Adenylyl Cyclases
Adrenergic beta-Agonists
Amino Acid Sequence
Animals
Cell Line
Cell Membrane
Cricetinae
Epinephrine
Humans
Iodocyanopindolol
Isoproterenol
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Norepinephrine

Pindolol

Receptors, Adrenergic, beta

Rhodopsin

Transfection

Source

Identifiers

PMID: 2881211
DOI: 10.1038/326073a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2881211-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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