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Article

Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer.

Cancer research - 1 Aug 2011

Xiong Fang, Wu Chen, Chang Jiang, Yu Dianke, Xu Binghe, Yuan Peng, Zhai Kan, Xu Jian, Tan Wen, Lin Dongxin

Abstract excerpt

Genetic variations in microRNAs (miRNA) that affect control of their target genes may alter individual susceptibilities to cancer. In this study, we took an in silico approach to identify single-nucleotide polymorphisms (SNP) within the 3'-untranslated region (UTR) of miRNA genes deregulated in human small-cell lung cancer (SCLC), and then investigated their associations with SCLC susceptibility in 666 SCLC...

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Source

Identifiers

PMID: 21676885
DOI: 10.1158/0008-5472.CAN-10-4407

Genes

MYC
ASCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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