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Article

Two independent signals, a nuclear localization signal and a Vp1-interactive signal, reside within the carboxy-35 amino acids of SV40 Vp3.

Virology - 1 Sept 1990

Gharakhanian E, Kasamatsu H

Abstract excerpt

The carboxy-terminal 35 amino acids (numbering 199 to 234) of SV40 Vp3 are essential for the nuclear localization of the protein as well as for its interactions with Vp1. Here, we describe studies directed at the further mapping of these two functions. Deletion and site-directed mutants of Vp3 were created within both a eukaryotic transfection and an SP6 transcription vector which encode Vp3. The subcellular...

Topics

Animals
Base Sequence
Capsid
Capsid Proteins
Cell Nucleus
Chromosome Mapping
Cloning, Molecular
Molecular Sequence Data
Mutation
Protein Biosynthesis
Protein Sorting Signals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rabbits

Simian virus 40

Structure-Activity Relationship

Transfection

Viral Proteins

Source

Identifiers

PMID: 2167562
DOI: 10.1016/0042-6822(90)90379-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2167562-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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