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Article

Functional complementation of nuclear targeting-defective mutants of simian virus 40 structural proteins

1 Dec 1994

Abstract excerpt

Structural proteins of simian virus 40 (SV40), Vp2 and Vp3 (Vp2/3) and Vp1, carry individual nuclear targeting signals, Vp3(198-206) (Vp2(316-324) and Vp1(1-8), respectively, which are encoded in different reading frames of an overlapping region of the genome. How signals coordinate nuclear targeting during virion morphogenesis was examined by using SV40 variants in which there is only one structural gene for Vp1...

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PMID: 7966613
DOI: 10.1128/jvi.68.12.8209-8216.1994

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