Article
Association of HLA genes with ankylosing spondylitis in Han population of eastern China.
Scandinavian journal of immunology - 1 Jun 2007
Fang M, Chen R, Cai Q, Duan S, Lv K, Cheng N, Sun S
Abstract excerpt
Ankylosing spondylitis (AS) is a chronic inflammatory disorder with a multifactorial genetic basis. HLA-B27 was reported with the greatest susceptibility to AS but did not act alone. The aim of this study was to search for other gene(s) associated with AS independently of HLA-B27 using 13 microsatellite markers spanning 1.5 Mb from locus TAP1 to HLA-Cw and a single-nucleotide polymorphism marker within...
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