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Article

Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ω-3 fatty acids: the Rotterdam study.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jun 2011

Ho Lintje, van Leeuwen Redmer, Witteman Jacqueline C M, van Duijn Cornelia M, Uitterlinden André G, Hofman Albert, de Jong Paulus T V M, Vingerling Johannes R, Klaver Caroline C W

Abstract excerpt

OBJECTIVE: To investigate whether dietary nutrients can reduce the genetic risk of early age-related macular degeneration (AMD) conferred by the genetic variants CFH Y402H and LOC387715 A69S in a nested case-control study. METHODS: For 2167 individuals (≥55 years) from the population-based Rotterdam Study at risk of AMD, dietary intake was assessed at baseline using a semiquantitative food frequency questionnaire...

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PMID: 21670343
DOI: 10.1001/archophthalmol.2011.141

Genes

CFH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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