Article
Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations.
Ophthalmology - 1 Mar 2014
Wang Jie Jin, Buitendijk Gabriëlle H S, Rochtchina Elena, Lee Kristine E, Klein Barbara E K, van Duijn Cornelia M, Flood Victoria M, Meuer Stacy M, Attia John, Myers Chelsea, Holliday Elizabeth G, Tan Ava G, Smith Wayne T, Iyengar Sudha K, de Jong Paulus T V M, Hofman Albert, Vingerling Johannes R, Mitchell Paul, Klein Ronald, Klaver Caroline C W
Abstract excerpt
OBJECTIVE: To examine effect modification between genetic susceptibility to age-related macular degeneration (AMD) and dietary antioxidant or fish consumption on AMD risk. DESIGN: Pooled data analysis of population-based cohorts. PARTICIPANTS: Participants from the Blue Mountains Eye Study (BMES) and Rotterdam Study (RS). METHODS: Dietary intakes of antioxidants (lutein/zeaxanthin [LZ], β-carotene, and vitamin...
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