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<i>Tudor domain containing 7</i> ( <i>Tdrd7</i> ) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis

13 Jun 2011

Abstract excerpt

In the male germline in mammals, chromatoid bodies, a specialized assembly of cytoplasmic ribonucleoprotein (RNP), are structurally evident during meiosis and haploidgenesis, but their developmental origin and regulation remain elusive. The tudor domain containing proteins constitute a conserved class of chromatoid body components. We show that tudor domain containing 7 (Tdrd7), the deficiency of which causes...

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PMID: 21670278
DOI: 10.1073/pnas.1015447108

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