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Article

RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis

11 Aug 2005

Abstract excerpt

Nuages are found in the germ cells of diverse organisms. However, nuages in postnatal male germ cells of mice are poorly studied. Previously, we cloned a germ cell-specific gene named Rnf17, which encodes a protein containing both a RING finger and tudor domains. Here, we report that RNF17 is a component of a novel nuage in male germ cells--the RNF17 granule, which is an electron-dense non-membrane bound...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 16093322
DOI: 10.1242/dev.02003

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RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesisPMID 16093322Read ↗

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The Role of Nanos in Germ Granules—Putative Posttranscriptional Regulation Hubs in Germ Cell Specification and Development Across SpeciesSemantic proximity Read ↗

Drosophila maelstrom ensures proper germline stem cell lineage differentiation by repressing microRNA-7.Semantic proximity Read ↗

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in miceSemantic proximity Read ↗

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MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.Semantic proximity Read ↗

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