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Article

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice

7 Mar 2011

Abstract excerpt

The Tudor domain-containing proteins (TDRDs) are an evolutionarily conserved family of proteins involved in germ cell development. We show here that in mice, TDRD5 is a novel component of the intermitochondrial cements (IMCs) and the chromatoid bodies (CBs), which are cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. Tdrd5-deficient males are sterile because of spermiogenic...

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PMID: 21383078
DOI: 10.1083/jcb.201009043

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TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in micePMID 21383078Read ↗

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