Article
Association between single-nucleotide polymorphisms in pre-miRNAs and the risk of asthma in a Chinese population.
DNA and cell biology - 1 Nov 2011
Su Xiao-Wei, Yang Yan, Lv Mei-Li, Li Li-Juan, Dong Wei, Miao-Liao, Gao Lin-Bo, Luo Hai-Bo, Yun-Liu, Cong Rui-Juan, Liang Wei-Bo, Li Ying-Bi
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in pre-miRNAs may alter microRNA (miRNA) expression levels or processing and contribute to susceptibility to a wide range of diseases. We investigated the correlation between four SNPs (rs11614913, rs3746444, rs2910164, and rs229283) in pre-miRNAs and the risk of asthma in 220 asthma patients and 540 controls using polymerase chain reaction-restriction fragment length...
Read the complete abstract on PubMed