Article
Genetic variants in miR-145 gene are associated with the risk of asthma in Taiwan.
Scientific reports - 7 Sept 2022
Wang Shou-Cheng, Tsai Chia-Wen, Chang Wen-Shin, Hsia Ning-Yi, Mong Mei-Chin, Wang Yun-Chi, Hsia Te-Chun, Gu Jian, Bau Da-Tian
Abstract excerpt
Asthma is a chronic airway inflammation disease and the diagnosis and treatment strategies remain difficult. MicroRNAs play important roles in many biological and pathological processes including asthma development. There is no study confirming the contribution of genetic variants in miR-145 to asthma etiology. We hypothesize that single nucleotide polymorphisms (SNPs) in the promoter region of miR-145 may be...
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