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Association between polymorphisms in pre-miRNA genes and risk of lung cancer in a Chinese non-smoking female population.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2016

Yin Zhihua, Cui Zhigang, Ren Yangwu, Xia Lingzi, Wang Qianqian, Zhang Ying, He Qincheng, Zhou Baosen

Abstract excerpt

BACKGROUND: MicroRNAs play important roles in the development of human chronic diseases including lung cancer. This is the first case-control study of lung cancer in a non-smoking female population in northeast China, to evaluate the roles of the polymorphisms in pre-miRNAs on risk of lung cancer. METHODS: The genotypes of six polymorphisms in miRNAs were determined in 575 patients with lung cancer and 608...

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PMID: 26973201
DOI: 10.1016/j.lungcan.2016.01.013

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