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Article

The natural resistance-associated macrophage protein from the protozoan parasite Perkinsus marinus mediates iron uptake.

Biochemistry - 26 Jul 2011

Lin Zhuoer, Fernández-Robledo José-Antonio, Cellier Mathieu F M, Vasta Gerardo R

Abstract excerpt

Microbial pathogens succeed in acquiring essential metals such as iron and manganese despite their limited availability because of the host's immune response. The eukaryotic natural resistance-associated macrophage proteins mediate uptake of divalent metals and, during infection, may compete directly for metal acquisition with the pathogens' transporters. In this study, we characterize the Nramp gene family of...

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PMID: 21661746
DOI: 10.1021/bi200343h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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