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Article

The correlation of hepatitis B virus pre-S mutation with mitochondrial D-loop mutations and common deletions in hepatocellular carcinoma.

Hepato-gastroenterology - 1 Jan 2000

Gwak Geum-Youn, Lee Dong Ho, Moon Tae Gun, Choi Moon Suk, Lee Joon Hyeok, Koh Kwang Cheol, Paik Seung Woon, Joh Jae-Won, Yoo Byung Chul

Abstract excerpt

BACKGROUND/AIMS: We investigated the correlation of HBV pre-S mutation with the sites and frequencies of mtDNA mutations in HCC patients. METHODOLOGY: Twenty-seven HBV-related HCC patients and 8 control patients were included. HBV DNA was extracted from sera and the HBV S coding region was analyzed. Direct sequencing of the mtDNA D-loop was performed in paired HCC and adjacent non-neoplastic liver tissues. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21661424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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