Article
Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Reed S I, Wittenberg C
Abstract excerpt
The Cdc28 protein kinase functions in the G1 to S phase transition of the cell cycle of the budding yeast Saccharomyces cerevisiae. This is in contrast with observations of the homologous protein kinase from a variety of metazoans, where activity and function are associated with the G2 to M phase transition. We present evidence that the Cdc28 protein kinase is also required for mitosis and that this function is...
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