Probability and time to fixation of an evolving sequence.

doi:10.1016/j.tpb.2015.06.001

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Article

Probability and time to fixation of an evolving sequence.

Theoretical population biology - 1 Sept 2015

Santiago Enrique

Abstract excerpt

The propagation of a sequence in a population is traced using a branching process model of Poisson distributions. The sequence, initially inserted in a location of the genome of a single individual, is under selective pressure and can undergo detrimental, beneficial or even neutral mutations that allow for adaptive possibilities in the future. The exact solution for the ultimate probability of fixation (u) of the...

Topics

Biological Evolution
Humans
Models, Genetic
Mutation
Poisson Distribution
Probability
Selection, Genetic
Time Factors

Source

Open in PubMed

Identifiers

PMID: 26095328
DOI: 10.1016/j.tpb.2015.06.001

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