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Article

Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region.

Biochemistry - 24 Jul 1990

Kane W H, Devore-Carter D, Ortel T L

Abstract excerpt

Human coagulation factor V is a protein cofactor that is an essential component of the prothrombinase complex. A full-length factor V cDNA has been subcloned into the mammalian expression vector pDX and used to transfect COS cells. Approximately 95 +/- 4% of the recombinant human factor V (rHFV) synthesized in COS cells is secreted into the culture medium. Forty-eight hours after transfection rHFV antigen levels...

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Identifiers

PMID: 2397212
DOI: 10.1021/bi00481a003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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