Establishing a genetic recombination map for murine coronavirus strain A59 complementation groups.

doi:10.1016/0042-6822(90)90530-5

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Article

Establishing a genetic recombination map for murine coronavirus strain A59 complementation groups.

Virology - 1 Aug 1990

Baric R S, Fu K, Schaad M C, Stohlman S A

Abstract excerpt

MHV-A59 temperature-sensitive mutants, representing one RNA+ and five RNA- complementation groups, were isolated and characterized by genetic recombination techniques. Maximum recombination frequencies occurred under multiplicities of infection greater than 10 each in which 99.99% of the cells we...

Topics

Animals
Chromosome Mapping
Genetic Complementation Test
Genetic Techniques
Kinetics
Mice
Murine hepatitis virus
Mutation
RNA, Viral
Recombination, Genetic
Temperature

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