Article
Sequential and spatially restricted interactions of assembly factors with an autotransporter beta domain.
Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2011
Ieva Raffaele, Tian Pu, Peterson Janine H, Bernstein Harris D
Abstract excerpt
Autotransporters are bacterial virulence factors that consist of an N-terminal extracellular ("passenger") domain and a C-terminal β barrel domain ("β domain") that resides in the outer membrane. Here we used an in vivo site-specific photocrosslinking approach to gain insight into the mechanism by which the β domain is integrated into the outer membrane and the relationship between β domain assembly and passenger...
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