Article
Roles of periplasmic chaperone proteins in the biogenesis of serine protease autotransporters of Enterobacteriaceae.
Journal of bacteriology - 1 Nov 2009
Ruiz-Perez Fernando, Henderson Ian R, Leyton Denisse L, Rossiter Amanda E, Zhang Yinghua, Nataro James P
Abstract excerpt
The serine protease autotransporters of Enterobacteriaceae (SPATEs) represent a large family of virulence factors. The prevailing model for autotransporter secretion comprises entry to the periplasm via the Sec apparatus, followed by an obscure series of steps in which the C terminus of the periplasmic species inserts into the outer membrane as a beta-barrel protein, accompanied by translocation of the passenger...
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