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Article

Enhanced gene replacement frequency in KU70 disruption strain of Stagonospora nodorum.

Microbiological research - 20 Mar 2012

Feng Jie, Li Weijiao, Hwang Sheau-Fang, Gossen Bruce D, Strelkov Stephen E

Abstract excerpt

To improve the efficiency of gene disruption in Stagonospora nodorum, the putative KU70 gene encoding the Ku70 protein involved in the nonhomologous end-joining double DNA break repair pathway was identified and deleted. The KU70 disruption strain showed no apparent defect in vegetable growth, conidiation and pathogenicity on wheat and barley compared with the wild-type strain. The effect of the absence of KU70...

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PMID: 21646005
DOI: 10.1016/j.micres.2011.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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