Article
[Discordance of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in non-small cell lung cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Jun 2011
Fang Qin, Zhang Liang, Wang Siyu, Ou Wei
Abstract excerpt
BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor (EGFR) gene mutation assay has been applied to select the chemosensitive patients for tyrosine kinase inhibitor (TKI) treatment widely. The aim of this study is to determine the discordance of EGFR mutations between primary and corresponding metastatic tumors in non-small cell lung cancer (NSCLC). METHODS: Thirty five paired primary tumors and...
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