Article
[Comparison of EGFR and KRAS status between primary non-small cell lung cancer and corresponding metastases: a systematic review and meta-analysis].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Sept 2010
Han Chengbo, Zou Huawei, Ma Jietao, Zhou Yang, Zhao Jianzhu
Abstract excerpt
BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor (EGFR) and KRAS status were particularly critical for the choice of first-line targeted therapy of non-small cell lung cancer (NSCLC), while the primary tumor and metastases might be different in the EGFR and KRAS gene status. The aim of this pooled analysis is to compare EGFR and KRAS status in matching primary NSCLC and metastases and further to guide...
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