Article
Discordance of molecular biomarkers associated with epidermal growth factor receptor pathway between primary tumors and lymph node metastasis in non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2009
Park Sarah, Holmes-Tisch Alison J, Cho Eun Yoon, Shim Young Mog, Kim Jinkook, Kim Hyo Song, Lee Jeeyun, Park Yeon Hee, Ahn Jin Seok, Park Keunchil, Jänne Pasi A, Ahn Myung-Ju
Abstract excerpt
INTRODUCTION: For the identification of the patients who most likely benefit from epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC), molecular assays are considered to be of paramount importance. Given the heterogeneity of NSCLC at the molecular level, this study was conducted to determine the discrepancy in EGFR mutations between primary tumors and the...
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