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Article

Quantification of EGFR mutations in primary and metastatic tumors in non-small cell lung cancer.

Journal of experimental & clinical cancer research : CR - 8 Jan 2014

Wei Bing, Yang Ke, Zhao Jiuzhou, Chang Yuxi, Ma Zihui, Dong Bing, Guo Yongjun, Ma Jie

Abstract excerpt

BACKGROUND: EGFR mutation detection has been widely applied in the prediction of TKIs therapy in Non-Small Cell Lung Cancer (NSCLC). Metastatic tumors rather than primary tumors were usually assayed for those patients in advanced stages. Although the difference of EGFR mutation status in primary and metastatic tumors has been reported, the quantitative difference (ratio of mutated EGFR among total EGFR) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24398248
DOI: 10.1186/1756-9966-33-5
PMCID: PMC3892091

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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