Article
Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: A case control study.
Atherosclerosis - 1 Jan 2017
Bos Sven, Duvekot Martijne H C, Ten Kate Gert-Jan R, Verhoeven Adrie J M, Mulder Monique T, Schinkel Arend F L, Nieman Koen, Watts Gerald F, Sijbrands Eric J G, Roeters van Lennep Jeanine E
Abstract excerpt
BACKGROUND AND AIMS: Statins reduce subclinical atherosclerosis and premature atherosclerotic cardiovascular disease (ASCVD) in patients with familial hypercholesterolemia (FH). However, some FH patients still develop ASCVD despite statin therapy. We compared subclinical atherosclerosis assessed by carotid plaque presence and intima media thickness (C-IMT), in long-term statin-treated FH patients and healthy...
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