Article
Differential resistance of insect sodium channels with kdr mutations to deltamethrin, permethrin and DDT.
Insect biochemistry and molecular biology - 1 Sept 2011
Burton Mark J, Mellor Ian R, Duce Ian R, Davies T G Emyr, Field Linda M, Williamson Martin S
Abstract excerpt
Knockdown resistance (kdr) in insects, caused by inherited nucleotide polymorphisms in the voltage-gated sodium channel (VGSC) gene, is a major threat to the efficacy of pyrethroid insecticides. Classic kdr, resulting from an L1014F substitution in the VGSC is now present in numerous pest species. Two other substitutions at the L1014 locus have also been reported, L1014S and L1014H. Here we have used expression...
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